TRPV4 agonist-1 (free base)
CAT:
804-HY-114400-03
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TRPV4 agonist-1 (free base)
- CAS Number: 2314467-59-7
- UNSPSC Description: TRPV4 agonist-1 free base is a transient receptor potential vanilloid 4 (TRPV4) agonist with an EC50 of 60 nM in the hTRPV4 Ca2+ assay[1].
- Target Antigen: TRP Channel
- Type: Reference compound
- Related Pathways: Membrane Transporter/Ion Channel;Neuronal Signaling
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/TRPV4_agonist-1.html
- Purity: 99.58
- Solubility: DMSO : 83.33 mg/mL (ultrasonic)
- Smiles: O=C1N(C2=CC=C(OC3=CC=C(F)C=C3)C=C2)C(N4CCN(C)CC4)=NC5=C(F)C=CC=C51
- Molecular Weight: 448.46
- References & Citations: [1]Atobe M, et al. Discovery of Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonists as Regulators of Chondrogenic Differentiation: Identification of Quinazolin-4(3 H)-ones and in Vivo Studies on a Surgically Induced Rat Model of Osteoarthritis. J Med Chem. 2019 Jan 28.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C, 3 years (Powder)
- Clinical Information: No Development Reported