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Recombinant Beta Secretase 2 (BACE2)

CAT: 0338-TRV-032342-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0338-TRV-032342-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9000-83-3
Product Name Alternative
AEPLC; ALP56; ASP1; ASP21; BAE2; CDA13; CEAP1; DRAP; Beta-Site APP Cleaving Enzyme 2; Aspartic-like protease 56 kDa; Aspartyl protease 1; Down region aspartic protease; Memapsin-1
Synonyms
Beta Secretase 2
UniProt
Q9JL18
Expression System
Prokaryotic expression
Host
E. coli
Tag
N-terminal His and GST Tag
Source
Prokaryotic expression
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
Field of Research
Enzyme & Kinase; Neuro science
Endotoxin
<1.0EU per 1μg (determined by the LAL method)
Purity
> 95%
Form
Freeze-dried powder
Buffer
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Calculated Molecular Weight
59.7kDa
Observed Molecular Weight
58kDa
Fragment
Glu156~Val407 (Accession # Q9JL18)
Isoelectric Point
5.5
Subcellular Location
Membrane; Single-pass type I membrane protein. Golgi apparatus. Endoplasmic reticulum. Endosome. Cell surfac
Product Name Synonym
Beta Secretase 2
Host or Source
E.coli
Organism Species
Mus musculus (Mouse)

UniProtKB · Q9JL18

Beta-secretase 2

BACE2_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q9JL18
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Bace2
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
3.4.23.45
Processing
Precursor
Secondary accessions
Q3TNS7, Q8C5E9, Q8C793, Q9R1P7
Protein keywords

Molecular function

Aspartyl proteaseHydrolaseProtease

PTM

Autocatalytic cleavageDisulfide bondGlycoproteinZymogen

Cellular component

Cell membraneEndoplasmic reticulumEndosomeGolgi apparatusMembrane

Technical term

Reference proteome

Domain

SignalTransmembraneTransmembrane helix

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