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Recombinant Cubilin (CUBN)

CAT: 0338-TRV-034704-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0338-TRV-034704-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9000-83-3
Product Name Alternative
IFCR; MGA1; gp280; Intrinsic Factor Cobalamin Receptor; 460 kDa receptor; Intestinal intrinsic factor receptor; Intrinsic factor-vitamin B12 receptor
Synonyms
Cubilin
UniProt
O70244
Expression System
Prokaryotic expression
Host
E. coli
Tag
N-terminal His Tag
Source
Prokaryotic expression
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
Field of Research
Signal transduction; Metabolic pathway; Nutrition metabolism; Dermatology
Endotoxin
<1.0EU per 1μg (determined by the LAL method)
Purity
> 90%
Form
Freeze-dried powder
Buffer
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Calculated Molecular Weight
13.5kDa
Observed Molecular Weight
16kDa
Fragment
Gly98~Cys207 (Accession # O70244)
Isoelectric Point
5.81
Subcellular Location
Cytoplasm
Product Name Synonym
Cubilin
Host or Source
E.coli
Organism Species
Rattus norvegicus (Rat)

UniProtKB · O70244

Cubilin

CUBN_RAT · Rattus norvegicus

View on UniProt ↗
Primary accession
O70244
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Cubn
Protein existence
1: Evidence at protein level
Organism
Rattus norvegicus (Rat)
Taxonomy ID
10116
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

Ligand

CalciumCobalaminCobaltMetal-binding

Cellular component

Cell membraneEndosomeLysosomeMembrane

Biological process

Cholesterol metabolismLipid metabolismProtein transportSteroid metabolismSterol metabolismTransport

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinPhosphoprotein

Technical term

Direct protein sequencingReference proteome

Domain

EGF-like domainRepeatSignal

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