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NOS2 antibody

CAT: 0710-FNab10777Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10777Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NOS2, also named as iNOS and NOS2A, produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. NO is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. NOS2 is a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. This antibody is specific to NOS2.
Synonyms
Nitric oxide synthase, inducible|Hepatocyte NOS (HEP-NOS) |Inducible NO synthase (Inducible NOS, iNOS) |NOS type II|Peptidyl-cysteine S-nitrosylase NOS2|NOS2|NOS2A
Gene ID
4843
UniProt
P35228
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Nitric oxide synthase 2, inducible
Target
NOS2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Neuroscience, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC

UniProtKB · P35228

Nitric oxide synthase, inducible

NOS2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35228
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NOS2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.14.13.39
Processing
—
Secondary accessions
A1L3U5, B7ZLY2, O60757, O94994, Q16263, Q16692, Q4TTS5, Q9UD42
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

CalciumFADFlavoproteinFMNHemeIronMetal-bindingNADPZinc

Molecular function

Calmodulin-bindingOxidoreductase

Cellular component

Cytoplasm

PTM

PhosphoproteinUbl conjugation

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