Dimethoate

• Description :

  Dimethoate is an organophosphate insecticide and acaricide. Dimethoate is an orally active acetylcholinesterase inhibitor. Dimethoate induces reactive oxygen species (ROS) . Dimethoate induces DNA damage and cell apoptosis in vivo. Dimethoate affect immune system in mice[1][2][3].

• UNSPSC :

  12352211

• Hazard Statement :

  H301+H311

• Target :

  Apoptosis; Cholinesterase (ChE) ; Insecticide; Reactive Oxygen Species (ROS)

• Type :

  Reference compound

• Related Pathways :

  Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; Others

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/dimethoate.html

• Purity :

  99.91

• Solubility :

  H2O : 10 mg/mL (ultrasonic)

• Smiles :

  S=P(OC)(SCC(NC)=O)OC

• Molecular Formula :

  C5H12NO3PS2

• Molecular Weight :

  229.26

• Precautions :

  H301+H311

• References & Citations :

  [1]Martínez-Morcillo S, et al. The organophosphorus pesticide dimethoate decreases cell viability and induces changes in different biochemical parameters of rat pancreatic stellate cells. Toxicol In Vitro. 2019 Feb;54:89-97.|[2]Nazam N, et al. Dimethoate Induces DNA Damage and Mitochondrial Dysfunction Triggering Apoptosis in Rat Bone-Marrow and Peripheral Blood Cells. Toxics. 2020 Oct 1;8 (4) :80.|[3]Aly NM, et al. Effect of dimethoate on the immune system of female mice. J Environ Sci Health B. 2000 Jan;35 (1) :77-86.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, stored under nitrogen)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 4

• CAS Number :

  [60-51-5]