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Dimethoate

CAT: 0804-HY-B1946-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1946-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dimethoate is an organophosphate insecticide and acaricide. Dimethoate is an orally active acetylcholinesterase inhibitor. Dimethoate induces reactive oxygen species (ROS) . Dimethoate induces DNA damage and cell apoptosis in vivo. Dimethoate affect immune system in mice[1][2][3].
CAS Number
60-51-5
UNSPSC
12352211
Hazard Statement
H301+H311
Target
Apoptosis; Cholinesterase (ChE) ; Insecticide; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dimethoate.html
Purity
99.91
Solubility
H2O : 10 mg/mL (ultrasonic)
Smiles
S=P(OC)(SCC(NC)=O)OC
Molecular Formula
C5H12NO3PS2
Molecular Weight
229.26
Precautions
H301+H311
References & Citations
[1]Martínez-Morcillo S, et al. The organophosphorus pesticide dimethoate decreases cell viability and induces changes in different biochemical parameters of rat pancreatic stellate cells. Toxicol In Vitro. 2019 Feb;54:89-97.|[2]Nazam N, et al. Dimethoate Induces DNA Damage and Mitochondrial Dysfunction Triggering Apoptosis in Rat Bone-Marrow and Peripheral Blood Cells. Toxics. 2020 Oct 1;8 (4) :80.|[3]Aly NM, et al. Effect of dimethoate on the immune system of female mice. J Environ Sci Health B. 2000 Jan;35 (1) :77-86.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Phase 4

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