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Fenquizone

CAT: 0804-HY-126179-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-126179-01Size:5 mg
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Description
Fenquizone (MG-13054) is an orally active diuretic. Fenquizone acts primarily on the diluting segment of the nephron cortex, similar to thiazide diuretics. Fenquizone demonstrates diuretic and natriuretic potency and duration of action comparable to thiazide diuretics but weaker than loop diuretics.​ Fenquizone reduces CH₂O without affecting TCH₂O, does not increase calcium/phosphate excretion, and has no loop or collecting duct effects. Fenquizone is used in the study of edema and hypertension[1].
CAS Number
20287-37-0
Product Name Alternative
MG-13054
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cardiovascular Disease; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/fenquizone.html
Purity
99.58
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(C1=CC2=C(NC(C3=CC=CC=C3)NC2=O)C=C1Cl)(N)=O
Molecular Formula
C14H12ClN3O3S
Molecular Weight
337.78
References & Citations
[1]Ferrando C, et al. On the pharmacological actions of a diuretic, fenquizone, with particular reference to its site of action. J Pharm Pharmacol. 1981 Apr;33 (4) :219-22.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
TRC-F249850-5MGFenquizone
450010Fenquizone-D5

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