ISRE (Luc) HEK293 Reporter Cell

• Background:

  ISRE is a marker of interferon stimulated genes (ISGs), which mainly include enzymes that can inhibit virus replication. Type I (such as IFN α and IFN β) and type III interferon (such as IFN-λ) can activate STAT1 and STAT2, and the activated STAT1, STAT2, and IRF9 form a protein complex called ISGF3. The ISGF3 protein complex binds to the promoter containing the ISRE element (interferon-stimulated response element) and activates the expression of related genes.

• Description:

  ISRE is a marker of interferon stimulated genes (ISGs), which mainly include enzymes that can inhibit virus replication. Type I (such as IFN α and IFN β) and type III interferon (such as IFN-λ) can activate STAT1 and STAT2, and the activated STAT1, STAT2, and IRF9 form a protein complex called ISGF3. The ISGF3 protein complex binds to the promoter containing the ISRE element (interferon-stimulated response element) and activates the expression of related genes.

• Host:

  HEK293

• Origin Species:

  Human

• Target:

  ISRE

• Tag:

  Luc

• Applications:

  • Screen for activators or inhibitors of Type I interferons.

• Format:

  Liquid

• Shipping Conditions:

  Dry ice

• Storage Conditions:

  Frozen in liquid nitrogen

• Package Size:

  1Vial*2

• Species:

  Human