Recombinant Mouse CXCL10 Protein (Sumo Tag)

• Background:

  Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types; such as monocytes; endothelial cells and fibroblasts; in response to IFN-γ. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles; such as chemoattraction for activated T-lymphocytes; inhibition of angiogenesis; and antitumor activity.

• Abbreviation:

  CXCL10

• Synonyms:

  IP-10; SCYB10; C7; Chemokine (C-X-C motif) ligand 10

• UniProt:

  P17515

• Accession Number:

  P17515

• Expression System:

  E.coli

• Tag:

  N-Sumo

• Sequence:

  Ile22-Pro98

• Field of Research:

  Immunology; Cancer; Signal Transduction

• Endotoxin:

  < 10 EU/mg of the protein as determined by the LAL method

• Purity:

  > 95% as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  21.4 kDa

• Observed Molecular Weight:

  30 kDa

• Formulation:

  Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

• Species:

  Mouse