Recombinant Human TGFβ1 Protein

• Background:

  Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.

• Abbreviation:

  TGFβ1

• Synonyms:

  LAP; Latency-associated peptide; TGF-beta-1; TGFB; Transforming growth factor beta-1 proprotein

• UniProt:

  P01137

• Accession Number:

  P01137

• Expression System:

  E.coli

• Tag:

  N-GST

• Sequence:

  Ala279-Ser390

• Field of Research:

  Immunology; Cardiovascular

• Endotoxin:

  < 10 EU/mg of the protein as determined by the LAL method.

• Purity:

  > 85% as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  36.8 kDa

• Observed Molecular Weight:

  40 kDa

• Species:

  Human