Recombinant Mouse Ccl8 Protein (Trx Tag)

• Background:

  CCL8, also known as Monocyte Chemoattractant Protein 2 (MCP-2), is an inflammatory CC chemokine that attracts monocytes, eosinophils and basophils. It is produced by many cell types and signals through interactions with an CCR1, CCR2, CCR3 and CCR5.

• Abbreviation:

  Ccl8

• Synonyms:

  Ccl8; CCL8_HUMAN; HC14; MCP-2; MCP-2 (6-76) ; Monocyte chemoattractant protein 2; Monocyte chemotactic protein 2; SCYA10; SCYA8; Small-inducible cytokine A8

• UniProt:

  Q9Z121

• Accession Number:

  Q9Z121

• Expression System:

  E. coli

• Tag:

  N-Trx

• Sequence:

  Gly24-Pro97

• Endotoxin:

  < 10 EU/mg of the protein as determined by the LAL method.

• Purity:

  > 90% as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  28.1 kDa

• Observed Molecular Weight:

  31 kDa

• Formulation:

  Lyophilized from a 0.2 µm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

• Species:

  Mouse