Recombinant Human CCL8/MCP-2 Protein
CAT:
763-PKSH033731-02
Size:
10 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Human CCL8/MCP-2 Protein
- Background: Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3; respectively. All three MCP proteins are monocyte chemoattractants. CCL8 is chemotactic for and activates many different immune cells; including mast cells; eosinophils and basophils; which are implicated in allergic response; and monocytes; T cells; and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors including CCR1; CCR2B and CCR5.
- Abbreviation: CCL8;MCP-2
- Synonyms: C-C Motif Chemokine 8, CCL8, HC14, MCP-2, MCP2, Monocyte Chemoattractant Protein 2, Monocyte Chemotactic Protein 2, SCYA10, SCYA8, Small-Inducible Cytokine A8
- CAS Number: 9000-83-3
- UniProt: P80075
- Accession Number: P80075
- Host: E. coli
- Origin Species: Human
- Tag: None
- Sequence: Gln24-Pro99
- Field of Research: immunology
- Purity: > 95 % as determined by reducing SDS-PAGE.
- Bioactivity: Not validated for activity
- Reconstitution: Please refer to the printed manual for detailed information.
- Molecular Weight: 12 kDa
- Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
- Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.