CD44 Monoclonal Antibody

CAT: 0763-AN200021P-01Size: 20 µLDry Ice: NoHazardous: No

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CAT#:0763-AN200021P-01Size:20 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

Abbreviation

CD44

UniProt

P16070

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD44 protein

Target

CDW; MIC; CSPG; Phagocytic glycoprotein; MDU; Pgp; CDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CD44; CD44 antigen; Epican; PGP-1; PGP-I; Phagocytic glycoprotein 1; Phagocytic glycoprotein I; H-CAM; CD44v; Pgp-1; EMCR III; CD44s; BA-1; CD 44; CD44 molecule; CD44 molecule (Indian blood group) ; CD44v9; Cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; hematopoietic cell E- and L-selectin ligand; Heparan sulfate proteoglycan; Hermes antigen; homing function and Indian blood group system; HSA; HUTCH1; Hyaluronate receptor; INLU-related p80 Glycoprotein; MGC10468; MUTCH1; Soluble CD44

Clonality

Monoclonal

Clone

9F3

Conjugation

Unconjugated

Applications

WB; IP

Field of Research

Immunology; Stem Cells; Cancer; Kits; Lysates; Other

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IP 0.2-1 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

82 kDa

Observed Molecular Weight

98 kDa

Isotype

IgG1

UniProtKB · P16070

CD44 antigen

CD44_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P16070
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: CD44
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: Precursor
Secondary accessions: A5YRN9, B6EAT9, D3DR12, D3DR13, O95370, P22511, Q04858, Q13419, Q13957, Q13958, Q13959, Q13960, Q13961, Q13967, Q13968, Q13980, Q15861, Q16064, Q16065, Q16066, Q16208, Q16522, Q86T72, Q86Z27, Q8N694, Q92493, Q96J24, Q9H5A5, Q9UC28, Q9UC29, Q9UC30, Q9UCB0, Q9UJ36

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

Blood group antigenReceptor

Biological process

Cell adhesion

Cellular component

Cell membraneCell projectionMembraneSecreted

PTM

Disulfide bondGlycoproteinPhosphoproteinProteoglycan

Domain

SignalTransmembraneTransmembrane helix

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Alternative Products

Catalog	Name
MB66049	CD44 monoclonal antibody
MB10701	CD44 monoclonal antibody