CD44 Polyclonal Antibody

• Background :

  CD44 is a type I transmembrane glycoprotein that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands. Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. This protein exists in multiple isoforms (with molecular weight ranging from 16 kDa to over 200 kDa) generated by alternative RNA splicing and undergoes extensive post-translational modifications.

• Abbreviation :

  CD44

• UniProt :

  P26051

• Host :

  Rabbit

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Recombinant Rat CD44 protein expressed by E.coli

• Target :

  LHR; BA-1; CD44 antigen; CD44 molecule; Cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; CSPG8; Epican; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor ; HCELL; HAS; HUTCH1; PGP-1; Phagocytic glycoprotein 1

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB

• Field of Research :

  Cancer; Immunology; Stem Cells

• Purification :

  Antigen Affinity Purification

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:1000

• Buffer :

  PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  51kDa

• Observed Molecular Weight :

  70-85kDa

• Isotype :

  IgG