CD34 Monoclonal Antibody

• Background:

  CD34, also known as gp105-120, is a type I monomeric sialomucin-like glycophosphoprotein with an approximate molecular weight of 105-120 kD. Selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nervous tissue, CD34 is a commonly used marker to identify human hematopoietic stem/progenitor cells. According to the differential sensitivity to enzymatic cleavage, four groups of epitopes of CD34 have been described. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands.

• Abbreviation:

  CD34

• UniProt:

  P28906

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Full length human CD34 expression plasmid

• Target:

  GIG; MORT; Hematopoietic progenitor cell antigen CD; Gp105; CD34; CD34 molecule; GIG3; MORT1; Gp105-120; My10; Hematopoietic progenitor cell antigen CD34; Mucosialin; CD34; CD34 molecule; GIG3; MORT1; RP11-328D5.2

• Clonality:

  Monoclonal

• Clone:

  6C6

• Conjugation:

  Unconjugated

• Applications:

  IHC-P

• Field of Research:

  Neuroscience; Immunology; Stem Cells; Cancer; Cardiovascular; Developmental Biology

• Purification:

  Protein A

• Concentration:

  1 mg/mL

• Dilution:

  IHC-P 1:30-1:100

• Buffer:

  0.2 μm filtered solution in PBS

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Isotype:

  IgG1