Ribocil-C

• Description :

  Ribocil-C is a highly selective inhibitor of bacterial riboflavin riboswitches.

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H320

• Target :

  Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/Ribocil-C.html

• Concentration :

  10mM

• Purity :

  99.69

• Solubility :

  DMSO : 110 mg/mL (ultrasonic)

• Smiles :

  O=C1C=C(C2=CC=CS2)NC([C@H]3CCCN(CC4=CN(C5=NC=CC=N5)C=N4)C3)=N1

• Molecular Formula :

  C21H21N7OS

• Molecular Weight :

  419.50

• Precautions :

  H315, H319, H320

• References & Citations :

  [1]Wang H, et al. Dual-Targeting Small-Molecule Inhibitors of the Staphylococcus aureus FMN Riboswitch DisruptRiboflavin Homeostasis in an Infectious Setting. Cell Chem Biol. 2017 May 18;24 (5) :576-588.|[2]Howe JA, et al. Selective small-molecule inhibition of an RNA structural element. Nature. 2015 Oct 29;526 (7575) :672-7.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1825355-56-3]