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(S) -Veludacigib

CAT: 0804-HY-153343A-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-153343A-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(S) -BAY 2965501 is the left-handed isomer of BAY 2965501. BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor. BAY 2965501 induces pERK activation. BAY 2965501 can be used for the research of cancer[1].
CAS Number
2732902-09-7
Product Name Alternative
(S) -BAY 2965501
UNSPSC
12352005
Target
DGK; ERK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; Metabolic Enzyme/Protease; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-bay-2965501.html
Concentration
10mM
Purity
99.43
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
NC([C@H](C)N(C1=CC=C(C=C1)F)C2=NC(N)=C(C(C3=CC=C(C=C3)OC)=O)S2)=O
Molecular Formula
C20H19FN4O3S
Molecular Weight
414.45
References & Citations
[1]Schubert N, et al. Phosphorylated extracellular signal-regulated kinase (pERK) activation in T effector cells as a target engagement biomarker for the DGK inhibitor BAY2965501 in clinical trials. Cancer Research, 2023, 83 (7_Supplement) : 2116-2116.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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