3-Acetyldeoxynivalenol-13C17

3-Acetyldeoxynivalenol-13C17

• CAS Number: 1217476-81-7
• UNSPSC Description: 3-Acetyldeoxynivalenol-13C17 is the 13C labeled 3-Acetyldeoxynivalenol (HY-N6685)[1]. 3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative[2], is a blood-brain barrier (BBB) permeable mycotoxin[3].
• Target Antigen: Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Others
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/3-acetyldeoxynivalenol-13c17.html
• Purity: 99.0
• Solubility: 10 mM in DMSO
• Smiles: [13CH3][13C@]12[13C@@]3([13C@@]([H])([13C@H](O[13C]([13CH3])=O)[13CH2]2)O[13C@]4([13C@]1([13CH2]O)[13C@H](O)[13C]([13C]([13CH3])=[13CH]4)=O)[H])[13CH2]O3
• Molecular Weight: 355.23
• References & Citations: [1]Kadota T, et al. Comparative study of deoxynivalenol, 3-acetyldeoxynivalenol, and 15-acetyldeoxynivalenolon intestinal transport and IL-8 secretion in the human cell line Caco-2. Toxicol In Vitro. 2013 Sep;27(6):1888-95.|[2]Behrens M, et al. Blood-Brain Barrier Effects of the Fusarium Mycotoxins Deoxynivalenol, 3Acetyldeoxynivalenol, and Moniliformin and Their Transfer to the Brain. PLoS One. 2015 Nov 23;10(11):e0143640.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220.
• Shipping Conditions: Blue Ice
• Storage Conditions: Solution, -20°C, protect from light, 2 years
• Clinical Information: No Development Reported