Mycophenolic acid-13C17

Mycophenolic acid-13C17

• CAS Number: 1202866-92-9
• UNSPSC Description: Mycophenolic acid-13C17 (Mycophenolate-13C17) is the 13C labeled Mycophenolic acid (HY-B0421). Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects.
• Target Antigen: Flavivirus; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Anti-infection;Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mycophenolic-acid-13c17.html
• Solubility: 10 mM in DMSO
• Smiles: [13CH3][13C]1=[13C]2[13C]([13C](O[13CH2]2)=O)=[13C]([13C]([13CH2]/[13CH]=[13C]([13CH3])/[13CH2][13CH2][13C](O)=O)=[13C]1O[13CH3])O
• Molecular Weight: 337.21
• References & Citations: [1]Sophie Domhan, et al. Molecular mechanisms of the antiangiogenic and antitumor effects of mycophenolic acid. Mol Cancer Ther. 2008 Jun;7(6):1656-68.|[2]Stephen R Welch, et al. Screening and Identification of Lujo Virus Inhibitors Using a Recombinant Reporter Virus Platform. Viruses. 2021 Jun 28;13(7):1255.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported