α-Tocopherol phosphate (disodium)

α-Tocopherol phosphate (disodium)

• CAS Number: 60934-46-5
• UNSPSC Description: α-Tocopherol phosphate (alpha-Tocopherol phosphate) disodium, a promising antioxidant, can protect against long-wave UVA1 induced cell death and scavenge UVA1 induced ROS in a skin cell model. α-Tocopherol phosphate disodium possesses therapeutic potential in the inhibition of apoptosis and increases the migratory capacity of endothelial progenitor cells under high-glucose/hypoxic conditions and promotes angiogenesis[1][2].
• Target Antigen: Apoptosis; Reactive Oxygen Species
• Type: Biochemical Assay Reagents
• Related Pathways: Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Cardiovascular Disease; Cancer
• Assay Protocol: https://www.medchemexpress.com/α-tocopherol-phosphate-disodium.html
• Purity: 98.01
• Solubility: DMSO : 4 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: CC1=C2C(CC[C@](C)(O2)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)=C(C(OP(O[Na])(O[Na])=O)=C1C)C
• Molecular Weight: 554.65
• References & Citations: [1]Saleh MM, et al. The photoprotective properties of α-tocopherol phosphate against long-wave UVA1 (385 nm) radiation in keratinocytes in vitro. Sci Rep. 2021 Nov 17;11(1):22400.|[2]Wu Z, et al. α-Tocopherol, especially α-tocopherol phosphate, exerts antiapoptotic and angiogenic effects on rat bone marrow-derived endothelial progenitor cells under high-glucose and hypoxia conditions. J Vasc Surg. 2018 Apr;67(4):1263-1273.e1.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: Phase 4