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AdTx1

CAT: 0804-HY-P1442Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P1442Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AdTx1 is a selective α1A-adrenoceptor antagonist (Ki: 0.35 nM) . AdTx1 can be used for research of benign prostatic hyperplasia[1].
UNSPSC
12352209
Target
Adrenergic Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/adtx1.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H]([C@H](O)C)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC2=CNC=N2)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N4[C@@H](CCC4)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCNC(N)=N)C(NC6)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC7=O)C(N[C@@H](C(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC8=CC=CC=C8)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CSSC[C@@H](C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)NC9=O)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C(N[C@H]9CCCCN)=O)=O)=O)=O)=O)NC%10=O)C(N%11[C@@H](CCC%11)C(N[C@@H]([C@@H](C)CC)C(N%12[C@@H](CCC%12)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC%13=CC=C(C=C%13)O)C(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(N[C@@H]([C@@H](C)CC)C(N[C@H]%10CC%14=CNC=N%14)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC6=O)C(N%15[C@@H](CCC%15)C(N[C@@H](CC(O)=O)C(NCC(N[C@@H](CCC(N)=O)C(N[C@@H](CC(N)=O)C(N[C@H]7CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(C)C)N
Molecular Formula
C310H481N87O100S8
Molecular Weight
7283.18
References & Citations
[1]Quinton L, et al. Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the alpha1A-adrenoceptor. Br J Pharmacol. 2010 Jan 1;159 (2) :316-25.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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