Monacolin J

• UNSPSC Description:

  Monacolin J is an inhibitor of cholesterol biosynthesis, and inhibits the activity of HMG-CoA reductase.

• Target Antigen:

  Autophagy; HMG-CoA Reductase (HMGCR)

• Type:

  Reference compound

• Related Pathways:

  Autophagy;Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/Monacolin_J.html

• Purity:

  99.22

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C1C[C@H](O)C[C@@H](CC[C@H]2[C@@H](C)C=CC3=C[C@H](C)C[C@H](O)[C@]23[H])O1

• Molecular Weight:

  320.429

• References & Citations:

  [1]Endo A, et al. Monacolins J and L, new inhibitors of cholesterol biosynthesis produced by Monascus ruber. J Antibiot (Tokyo). 1985 Mar;38(3):420-2.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  79952-42-4