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Mafenide (hydrochloride)

CAT: 0804-HY-B0614B-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0614B-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mafenide hydrochloride is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide hydrochloride shows activity against both Gram-positive and Gram-negative organisms, including Pseudomonas aeruginosa, via inhibition of nucleotide synthesis[1][2].
CAS Number
138-37-4
UNSPSC
12352005
Hazard Statement
H317
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Mafenide-hydrochloride.html
Purity
99.97
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C(CN)C=C1)(N)=O.[H]Cl
Molecular Formula
C7H11ClN2O2S
Molecular Weight
222.70
Precautions
H317
References & Citations
[1]Haynes, B.W., Jr., Mafenide acetate in burn treatment. N Engl J Med, 1971. 284 (23) : p. 1324.|[2]Ashkan Afshari, et al. The Effective Duration of Antimicrobial Activity of Mafenide Acetate After Reconstitution. J Burn Care Res. 2018 Aug 17;39 (5) :736-738.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched

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