Mafenide (Acetate)

• UNSPSC Description:

  Mafenide Acetate is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide Acetate shows activity against both Gram-positive and Gram-negative organisms, including Pseudomonas aeruginosa, via inhibition of nucleotide synthesis[1][2].

• Target Antigen:

  Antibiotic; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/Mafenide-Acetate.html

• Purity:

  99.91

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)|H2O : ≥ 100 mg/mL

• Smiles:

  O=S(C1=CC=C(CN)C=C1)(N)=O.CC(O)=O

• Molecular Weight:

  246.28

• References & Citations:

  [1]Haynes, B.W., Jr., Mafenide acetate in burn treatment. N Engl J Med, 1971. 284(23): p. 1324.|[2]Ashkan Afshari, et al. The Effective Duration of Antimicrobial Activity of Mafenide Acetate After Reconstitution. J Burn Care Res. 2018 Aug 17;39(5):736-738.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  Launched

• CAS Number:

  13009-99-9