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Chrexanthomycin C

CAT: 0804-HY-N10579Size: InquireDry Ice: NoHazardous: No
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CAT#:0804-HY-N10579Size:Inquire
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3030587-55-1
UNSPSC Description
Chrexanthomycin C is an orally active marine natural product with remarkable bioactivities. Chrexanthomycin C has binding affinity for DNA (G4C2)4 G4 with a Kd value of 2.8 mM. Chrexanthomycin C can be used for the research of neurodegenerative disease such as amyotrophic lateral sclerosis (ALS)[1].
Target Antigen
DNA/RNA Synthesis
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/chrexanthomycin-c.html
Solubility
10 mM in DMSO
Smiles
OC1=C2C3=C(O)C(C(O)=O)=C(CC(C)=O)C=C3CCC2=C(C4=C1C(C5=CC=CC(O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)C(O)=O)=C5O4)=O)O
Molecular Weight
638.53
References & Citations
[1]Aifang Cheng, et al. Selective C9orf72 G-Quadruplex-Binding Small Molecules Ameliorate Pathological Signatures of ALS/FTD Models. Journal of Medicinal Chemistry Article ASAP.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

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