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NCGC00262650

CAT: 0804-HY-126425-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-126425-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NCGC00262650 is a potent apical membrane antigen 1-rhoptry neck protein 2 (AMA1-RON2) interaction inhibitor. NCGC00262650 can block entry of merozoites into red blood cells with an IC50 of 9.8 μM[1].
CAS Number
344359-25-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ncgc00262650.html
Purity
99.22
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
NC1=C2C(N(C3CCCC3)C=C2C4=CC=C(OC)C=C4)=NC=N1
Molecular Formula
C18H20N4O
Molecular Weight
308.38
Precautions
H302, H315, H319
References & Citations
[1]Srinivasan P, et, al. Disrupting malaria parasite AMA1-RON2 interaction with a small molecule prevents erythrocyte invasion. Nat Commun. 2013;4:2261.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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