MID-1

CAT: 0804-HY-115461-01Size: 5 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-115461-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction. MID-1 disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake[1].

CAS Number

312608-54-1

Product Name Alternative

MLV-6976; NC-1209, MLV-6976 (hydrochloride); NC-1200 (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Insulin Receptor

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/mid-1.html

Purity

99.36

Solubility

DMSO : 31.25 mg/mL (ultrasonic)

Smiles

O=C(NC1=NC=C([N+]([O-])=O)S1)C2=CC=C(OCC)C=C2

Molecular Formula

C12H11N3O4S

Molecular Weight

293.30

Precautions

H302, H315, H319, H335

References & Citations

[1]Lee H, et, al. MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) Interaction Disruptor Sensitizes Insulin Signaling in Skeletal Muscle. J Biol Chem. 2016 Dec 23;291 (52) :26627-26635.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Related Products

Catalog	Name
HY-Y1911-01	Mid-chain triglyceride of caprylic/caprolic acid
HY-N6838-01	1,1,1,1-Kestohexaose
HY-157129	AMPK-α1β1γ1 activator 1
HY-133623	1,1,1-Tribromoacetone
HY-149536	TWIK-1/TREK-1-IN-1
HY-W160628S	1,1,1-Trimethoxypropane-d5
HY-133630-01	1-Bromo-1,1-dichloroacetone
HY-133629	1,1,1,3-Tetrachloroacetone
HY-W881439-01	1- (1,1-Dimethylethyl) tridecanedioate
HY-W032015S1	1-Bromooctane-1,1-d2

Alternative Products

Catalog	Name
BA8980-5	MID-1
T32673	Leucottetraoxy MID
PC35107	Mid-brain
MBS766206-01	Rat N-MID-OT (N-MID Osteocalcin)
MBS620328-01	Endophilin 1, Mid, SH3 Domain
KT-101406	Dog N MID Osteocalcin (N-MID-OC) ELISA
CYC-1	1 well reservoir, 190ml; mid skirt
MBS6473895-01	Endophilin 1, Mid, SH3 Domain-PE
MBS6473889-01	Endophilin 1, Mid, SH3 Domain (HRP)
MBS6473887-01	Endophilin 1, Mid, SH3 Domain (Biotin)

MID-1

Related Products

Alternative Products

Popular Products