RegisterLogin

Fluorene

CAT: 0804-HY-W026772-01Size: 500 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W026772-01Size:500 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Fluorene is an orally active polycyclic aromatic hydrocarbon (PAH) and a precursor to other fluorene-based compounds. Fluorene and its derivatives serve as dye precursors for fluorene synthesis. In A549 cells, Fluorene induces oxidative stress and inflammatory responses by increasing ROS and SOD generation, exacerbating lipid peroxidation, modulating antioxidant enzyme activity, and upregulating the expression of pro-inflammatory factors TNF-α and IL-6. In vivo, Fluorene exhibits anxiolytic activity. Fluorene holds potential for research in inflammation and neurological disorders[1][2][3].
CAS Number
[86-73-7]
UNSPSC
12171500
Hazard Statement
H360, H410
Target
Fluorescent Dye; Interleukin Related; Reactive Oxygen Species (ROS) ; SOD; TNF Receptor
Type
Dye Reagents
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/fluorene.html
Purity
99.35
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
C1(C=CC=C2)=C2CC3=C1C=CC=C3
Molecular Formula
C13H10
Molecular Weight
166.22
Precautions
H360, H410
References & Citations
[1]Paul Olusegun Bankole, et al. Biodegradation of fluorene by the newly isolated marine-derived fungus, Mucor irregularis strain bpo1 using response surface methodology. Ecotoxicol Environ Saf. 2021 Jan 15;208:111619.|[2]Guo H, et al. Oxidative stress and inflammatory effects in human lung epithelial A549 cells induced by phenanthrene, fluorene, and their binary mixture. Environ Toxicol. 2021 Jan;36 (1) :95-104.|[3]Peiffer J, et al. Behavioral toxicity and physiological changes from repeated exposure to fluorene administered orally or intraperitoneally to adult male Wistar rats: A dose–response study[J]. Neurotoxicology, 2016, 53: 321-333.
Shipping Conditions
Room Temperature
Storage Conditions
RT, protect from light
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

Related Products

CatalogName
HY-32181-01Fluorenone
HY-W016388-019-Fluorenol
HY-W019922-01Magnesium fluoride
HY-W019962-01Calcium fluoride
HY-B1766Sodium Fluoride
HY-21190-01Perfluorobutylsulfonyl fluoride
HY-32181S-01Fluorenone-d8
HY-Y0415Tetraethylammonium (fluoride)
HY-21195-01Perfluorohexylsulfonyl fluoride
HY-W016388R-019-Fluorenol (Standard)

Alternative Products

CatalogName
RG-A262241-01Fluorene
012128Fluorene-13C6
TRC-F462003-100MGFluorene-D10
01234 00100Fluorene 98%
OR18343-019H-Fluorene
094025-01Fluorene for Synthesis

Popular Products