Products for Research Use Only
RegisterLogin

Sennoside B

CAT: 0804-HY-N0366-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0366-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Sennoside B is a potent and orally active platelet-derived growth factor (PDGF) inhibitor. Sennoside B inhibits cell proliferation and the expression of phosphorylation of PDGFR-β, STAT-5, AKT and ERK induced by PDGF-BB. Sennoside B shows gastroprotective activities. Sennoside B has the potential for the research of gastritis[1][2].
CAS Number
128-57-4
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
PDGFR
Type
Natural Products
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sennoside-b.html
Purity
99.23
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@@H](O)[C@H](OC2=C(C(C(C(O)=CC(C(O)=O)=C3)=C3[C@]4([C@@]5(C(C=CC=C6O[C@H]7[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O7)=C6C(C8=C5C=C(C(O)=O)C=C8O)=O)[H])[H])=O)C4=CC=C2)O[C@H](CO)[C@H]1O
Molecular Formula
C42H38O20
Molecular Weight
862.74
Precautions
H315, H319, H335
References & Citations
[1]Hwang IY, et al. Gastroprotective Activities of Sennoside A and Sennoside B via the Up-Regulation of Prostaglandin E2 and the Inhibition of H (+) /K (+) -ATPase. Biomol Ther (Seoul) . 2015 Sep;23 (5) :458-64.|[2]Chen YC, et al. Sennoside B inhibits PDGF receptor signaling and cell proliferation induced by PDGF-BB in human osteosarcoma cells. Life Sci. 2009 Jun 19;84 (25-26) :915-22.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-N12281-01Sennoside
HY-N0365-01Sennoside A
HY-N1972-01Sennoside C
HY-N1973-01Sennoside D
HY-N0365R-01Sennoside A (Standard)
HY-N1973RSennoside D (Standard)
HY-N1972RSennoside C (Standard)
HY-P991290-01IRAB-B
HY-P11337Scyptolin B
HY-N8339Decatromicin B

Alternative Products

CatalogName
MS08136-01Sennoside A

Popular Products