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Trospium (chloride)

CAT: 0804-HY-B0461-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0461-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Trospium chloride is an orally active, specific and competitive antagonist of muscarinic cholinergic receptors (mAChRs), with antimuscarinic activity. Trospium chloride binds to muscarinic receptors M1, M2 and M3 with high affinity, but not nicotinic, cholinergic receptors[1][2].
CAS Number
10405-02-4
UNSPSC
12352005
Hazard Statement
H302
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Trospium-chloride.html
Purity
99.93
Solubility
DMSO : 25 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL
Smiles
[H][C@@]12CC[C@@](C[C@@H](OC(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)=O)C2)([H])[N+]15CCCC5.[Cl-]
Molecular Formula
C25H30ClNO3
Molecular Weight
427.96
Precautions
H302
References & Citations
[1]David RP Guay. Trospium chloride: an update on a quaternary anticholinergic for treatment of urge urinary incontinence. Ther Clin Risk Manag. 2005 Jun; 1 (2) : 157–167.|[2]Eric S Rovner, et al. Trospium chloride in the management of overactive bladder. Drugs. 2004;64 (21) :2433-46.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
MAChR1; mAChR2; mAChR3

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