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ROS151

CAT: 0804-HY-159943Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-159943Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ROS151 is an AChE inhibitor, with IC50s of 14 nM (hAChE), 1.68 μM (eqBChE), 8.17 μM (hFAAH) respectively. ROS151 is also a chelator of Fe3+ and Cu2+. ROS151 can be used for research of Alzheimer's disease[1].
UNSPSC
12352101
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ros151.html
Smiles
O=C(N(C)C)OC1=CC=CC(CNC(COC2=CC(F)=CC=C2[N+]([O-])=O)=O)=C1
Molecular Formula
C18H18FN3O6
Molecular Weight
391.35
References & Citations
[1]Leuci R, et al. Rivastigmine structure-based hybrids as potential multi-target anti-Alzheimer's drug candidates. Bioorg Chem. 2024 Dec;153:107895.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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