ROS1-IN-1

CAT: 0804-HY-150974Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-150974Size:1 Each

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Description

ROS1-IN-1 (Compound 31) is a potent and selective ROS1 kinase inhibitor with an IC50 of 0.097 μM[1].

CAS Number

2883232-34-4

UNSPSC

12352005

Target

ROS Kinase

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ros1-in-1.html

Solubility

10 mM in DMSO

Smiles

CC1=NC(N(CC2=CC=C(C(Cl)=C2)C#N)C)=NC(NC3=NC=CS3)=C1

Molecular Formula

C17H15ClN6S

Molecular Weight

370.86

References & Citations

[1]Petrović D, et al. Virtual Screening in the Cloud Identifies Potent and Selective ROS1 Kinase Inhibitors. J Chem Inf Model. 2022 Aug 3.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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