FN-439 (TFA)
CAT:
804-HY-100210A-01
Size:
5 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
FN-439 (TFA)
- UNSPSC Description: FN-439 TFA is a selective collagenase-1 inhibitor. FN-439 TFA inhibits collagenase-1 with an IC50 value of 1 μM. FN-439 TFA can be used for the research of cancer and inflammation[1][2].
- Target Antigen: MMP
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: COVID-19-immunoregulation
- Field of Research: Cancer; Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/fn-439-tfa.html
- Purity: 99.61
- Solubility: H2O : 250 mg/mL (ultrasonic)
- Smiles: OC(C(F)(F)F)=O.ONC([C@@H](C)NC([C@@H](CC(C)C)NC([C@H]1N(CCC1)C(CNC(C2=CC=C(C=C2)N)=O)=O)=O)=O)=O
- Molecular Weight: 604.58
- References & Citations: [1]U Benbow, et al. Human breast cancer cells activate procollagenase-1 and invade type I collagen: invasion is inhibited by all-trans retinoic acid. Clin Exp Metastasis. 1999 May;17(3):231-8.|[2]H Anan, et al. Effects of a combination of an antibacterial agent (ofloxacin) and a collagenase inhibitor (FN-439) on the healing of rat periapical lesions. J Endod. 1996 Dec;22(12):668-73.
- Shipping Conditions: Blue Ice
- Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
- Clinical Information: No Development Reported