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FN-1501-propionic acid

CAT: 0804-HY-130981Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-130981Size:1 Each
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Description
FN-1501-propionic acid is a CDK2/9 ligand for PROTAC. FN-1501-propionic acid and a CRBN ligand have been used to design PROTAC CDK2/9 degrader.
CAS Number
2408642-48-6
UNSPSC
12352005
Target
CDK; Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fn-1501-propionic-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCC(N1CCN(CC2=CC=C(NC(C3=NNC=C3NC4=C5C(NC=C5)=NC=N4)=O)C=C2)CC1)=O
Molecular Formula
C25H27N9O4
Molecular Weight
517.54
References & Citations
[1]Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2019 Dec 6;187:111952.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK2; CDK9

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