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Tibenelast sodium

CAT: 0804-HY-101705-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101705-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tibenelast sodium is a phosphodiesterase inhibitor.
CAS Number
105102-18-9
Product Name Alternative
LY 186655
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Tibenelast_(sodium).html
Purity
99.66
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CC2=CC(OCC)=C(OCC)C=C2S1)[O-].[Na+]
Molecular Formula
C13H13NaO4S
Molecular Weight
288.29
References & Citations
[1]Schwertschlag US, et al. Effect of tibenelast (a phosphodiesterase inhibitor) and theophylline on isoproterenol-stimulated heart rate, cyclic AMP and norepinephrine levels. Pharmacology. 1993;46 (3) :142-7.|[2]Ho PP, et al. Tibenelast, 5,6-diethoxybenzo (B) thiophene-2-carboxylic acid, sodium salt (LY186655), is an orally active anti-asthma compound in the guinea pig. Life Sci. 1990;46 (13) :917-25.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 2