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L-656224

CAT: 0804-HY-113826Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-113826Size:1 Each
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Description
L-656224 is an orally active, potent and selective inhibitor of leukotriene biosynthesis in intact rat and human leukocytes and CXBG mastocytoma cells (IC50 values, 18-240 nM) and of human leukocyte and porcine leukocyte 5-lipoxygenase (IC50, 4 x 10-7 M) . L-656224 is promising for research of asthma and peripheral analgesic agents[1].
CAS Number
102612-16-8
UNSPSC
12352005
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/l-656224.html
Smiles
ClC1=CC(CCC)=C(C2=C1OC(CC3=CC=C(C=C3)OC)=C2C)O
Molecular Formula
C20H21ClO3
Molecular Weight
344.83
References & Citations
[1]Belanger P, et al. L-656,224 (7-chloro-2-[ (4-methoxyphenyl) methyl]-3- methyl-5-propyl-4-benzofuranol) : a novel, selective, orally active 5-lipoxygenase inhibitor. Can J Physiol Pharmacol. 1987 Dec;65 (12) :2441-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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