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Recombinant Human CD79A Protein, C-His

CAT: 1676-PR01874Size: 10μg/50μg/500μg/1mgDry Ice: NoHazardous: No
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CAT#:1676-PR01874Size:10μg/50μg/500μg/1mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD79A (also known as Mb-1, Ig alpha and B cell antigen receptor complex-associated protein alpha-chain) is a 30-40 kDa member of the Ig-Superfamily. Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
Product Name Alternative
CD79A antigen; CD79a antigen; CD79A; MB1; MB-1
Accession Number
P11912
Tag
C-6His
Source
HEK293 Cells
Endotoxin
<1 EU/μg as determined by LAL test.
Purity
>95% as determined by reducing SDS-PAGE.
Form
Lyophilized
Reconstitution
Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 μg/mL.
Molecular Weight
13.4 KDa
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Storage Conditions
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Protein Length
Leu33-Arg143
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Species
Human

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