L-Methionine

• Description :

  L-Methionine is an L-isomer of orally active Methionine, an essential amino acid. Methionine is a strong liver antidote that acts as a liver protector. L-Methionine can inhibit cell proliferation and induce cell apoptosis. L-Methionine has antitumor and antioxidant activity[1][2][3].

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Apoptosis; Endogenous Metabolite; Keap1-Nrf2

• Type :

  Natural Products

• Related Pathways :

  Apoptosis; Metabolic Enzyme/Protease; NF-κB

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Cancer; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/L-Methionin.html

• Purity :

  99.90

• Solubility :

  H2O : 10 mg/mL (ultrasonic)

• Smiles :

  N[C@@H](CCSC)C(O)=O

• Molecular Formula :

  C5H11NO2S

• Molecular Weight :

  149.22

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Benavides MA, et al. L-Methionine inhibits growth of human pancreatic cancer cells. Anticancer Drugs. 2014 Feb;25 (2) :200-3.|[2]Erdmann K, et al. L-methionine reduces oxidant stress in endothelial cells: role of heme oxygenase-1, ferritin, and nitric oxide. AAPS J. 2005 Aug 29;7 (1) :E195-200.|[3]Wang Z, et al. l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats. J Sci Food Agric. 2019 Aug 15;99 (10) :4849-4862.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  Launched

• Isoform :

  Human Endogenous Metabolite; Microbial Metabolite

• CAS Number :

  [63-68-3]