Resorufin

• Description:

  Resorufin (NSC 12097) is a highly fluorescent pink dye. Resorufin shows favorable properties such as water solubility, red-shifted absorption/emission signals. Resorufin is used for the detection of ROS/RNS and a second analyte[1][2].

• Product Name Alternative:

  NSC 12097

• UNSPSC:

  12171500

• Hazard Statement:

  H315, H319, H335

• Target:

  Fluorescent Dye; Reactive Oxygen Species (ROS)

• Type:

  Dye Reagents

• Related Pathways:

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Resorufin.html

• Purity:

  99.0

• Solubility:

  0.5 M NaOH : 4.38 mg/mL (ultrasonic; warming; adjust pH to 13 with 0.5 M NaOH; heat to 60°C) |DMSO : < 1 mg/mL (ultrasonic) |Ethanol : < 1 mg/mL (ultrasonic)

• Smiles:

  O=C1C=CC2=NC3=C (OC2=C1) C=C (C=C3) O

• Molecular Formula:

  C12H7NO3

• Molecular Weight:

  213.19

• Precautions:

  H315, H319, H335

• References & Citations:

  [1]Odyniec ML , et al. 'AND'-based fluorescence scaffold for the detection of ROS/RNS and a second analyte. Chem Commun (Camb) . 2018 Jul 26;54 (61) :8466-8469.|[2]Almammadov T, et al. Resorufin Enters the Photodynamic Therapy Arena: A Monoamine Oxidase Activatable Agent for Selective Cytotoxicity. ACS Med Chem Lett. 2020 Nov 23;11 (12) :2491-2496.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  635-78-9