Resorufin

• Description :

  Resorufin (NSC 12097) is a highly fluorescent pink dye. Resorufin shows favorable properties such as water solubility, red-shifted absorption/emission signals. Resorufin is used for the detection of ROS/RNS and a second analyte[1][2].

• Product Name Alternative :

  NSC 12097

• UNSPSC :

  12171500

• Hazard Statement :

  H315, H319, H335

• Target :

  Fluorescent Dye; Reactive Oxygen Species (ROS)

• Type :

  Dye Reagents

• Related Pathways :

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Resorufin.html

• Purity :

  99.0

• Solubility :

  0.5 M NaOH : 4.38 mg/mL (ultrasonic; warming; adjust pH to 13 with 0.5 M NaOH; heat to 60°C) |DMSO : < 1 mg/mL (ultrasonic) |Ethanol : < 1 mg/mL (ultrasonic)

• Smiles :

  O=C1C=CC2=NC3=C(OC2=C1)C=C(C=C3)O

• Molecular Formula :

  C12H7NO3

• Molecular Weight :

  213.19

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]Odyniec ML , et al. 'AND'-based fluorescence scaffold for the detection of ROS/RNS and a second analyte. Chem Commun (Camb) . 2018 Jul 26;54 (61) :8466-8469.|[2]Almammadov T, et al. Resorufin Enters the Photodynamic Therapy Arena: A Monoamine Oxidase Activatable Agent for Selective Cytotoxicity. ACS Med Chem Lett. 2020 Nov 23;11 (12) :2491-2496.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported

• CAS Number :

  [635-78-9]