Apiole (Standard)

• Description:

  Apiole (Standard) is the analytical standard of Apiole. This product is intended for research and analytical applications. Apiole is an anti-tumor agent that induces apoptosis and inhibits human colon cancer cells by inducing G0/G1 cell cycle arrest. Apiole also significantly inhibited colon tumor development in an in vivo mouse xenograft model[1][2].

• UNSPSC:

  12352005

• Target:

  Apoptosis; Reference Standards

• Type:

  Reference Standards

• Related Pathways:

  Apoptosis; Others

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/apiole-standard.html

• Smiles:

  C=CCC1=CC(OC)=C(OCO2)C2=C1OC

• Molecular Formula:

  C12H14O4

• Molecular Weight:

  222.24

• References & Citations:

  [1]Wu KH, et al. Study of the antitumor mechanisms of apiole derivatives (AP-02) from Petroselinum crispum through induction of G0/G1 phase cell cycle arrest in human COLO 205 cancer cells. BMC Complement Altern Med. 2019 Jul 27;19 (1) :188.|[2]Wei PL, et al. The in vivo antitumor effects on human COLO 205 cancer cells of the 4,7-dimethoxy-5- (2-propen-1-yl) -1,3-benzodioxole (apiole) derivative of 5-substituted 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-1) isolated from the fruiting body of Antrodia camphorate. J Cancer Res Ther. 2012 Oct-Dec;8 (4) :532-6.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [523-80-8]