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Implitapide

CAT: 0804-HY-106130-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-106130-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Implitapide (AEGR 427) is a microsomal triglyceride transfer protein (MTP) inhibitor.
CAS Number
177469-96-4
Product Name Alternative
AEGR 427
UNSPSC
12352005
Target
Microsomal Triglyceride Transfer Protein (MTP)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Implitapide.html
Purity
99.87
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=C(C2=C3C=CC=C2)C(N3CC4=CC=C([C@H](C5CCCC5)C(N[C@H](C6=CC=CC=C6)CO)=O)C=C4)=NC(C)=C1
Molecular Formula
C35H37N3O2
Molecular Weight
531.69
References & Citations
[1]Ueshima K, et al. Implitapide, a microsomal triglyceride transfer protein inhibitor, reduces progression of atherosclerosis in apolipoprotein E knockout mice fed a Western-type diet: involvement of the inhibition of postprandial triglyceride elevation. Biol Pharm Bull. 2005 Feb;28 (2) :247-52.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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