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Vamicamide

CAT: 0804-HY-U00079A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-U00079A-01Size:1 mg
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Description
Vamicamide (FK-176) is an orally active competitive mAChR antagonist that inhibits contractions induced by cholinergic nerve stimulation by preventing mAChR agonists from binding to mAChR. Vamicamide exhibits a good anti-bladder spasm effect, with a pA2 value of 6.82 in bladder tissue. Vamicamide can be used in research within the field of neurological diseases[1].
CAS Number
132373-81-0
Product Name Alternative
FK-176
UNSPSC
12352005
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vamicamide.html
Smiles
O=C(N)[C@@](C1=CC=CC=C1)(C[C@H](N(C)C)C)C2=NC=CC=C2
Molecular Formula
C18H23N3O
Molecular Weight
297.39
References & Citations
[1]Oyasu H, et al. Urinary bladder-selective action of the new antimuscarinic compound vamicamide. Arzneimittelforschung. 1994 Nov;44 (11) :1242-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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