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Clavulanic acid

CAT: 0804-HY-A0256-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-A0256-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Clavulanic acid is a naturally occurring powerful bacterial β-lactamases inhibitor for research of infections caused by bacteria, including infections of the ears. Clavulanic acid is active against a wide spectrum of gram-positive and gram-negative bacterias[1].
CAS Number
58001-44-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial; Beta-lactamase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/clavulanic-acid.html
Purity
99.76
Solubility
DMSO : 13.33 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 7 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C([C@@H](/C(O[C@]1([H])C2)=C/CO)N1C2=O)O
Molecular Formula
C8H9NO5
Molecular Weight
199.16
Precautions
H302, H315, H319, H335
References & Citations
[1]Parag S Saudagar, et al. Clavulanic acid: a review. Biotechnol Adv. Jul-Aug 2008;26 (4) :335-51|[2]Neu HC, et al. Clavulanic acid, a novel inhibitor of beta-lactamases. Antimicrob Agents Chemother. 1978 Nov;14 (5) :650-5.|[3]Beceiro A, et al. In vitro activity and in vivo efficacy of clavulanic acid against Acinetobacter baumannii. Antimicrob Agents Chemother. 2009 Oct;53 (10) :4298-304.|[4]Soyocak A, et al. Tannic acid exhibits anti-inflammatory effects on formalin-induced paw edema model of inflammation in rats. Hum Exp Toxicol. 2019 Nov;38 (11) :1296-1301.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β-lactam
Citation 01
Eur J Pharmacol. 2024 Dec 5:984:177017.|Genomics. 2022 Nov;114 (6) :110527.|Int J Mol Sci. 2023 Oct 27;24 (21) :15657.|J Antimicrob Chemother. 2025 Nov 5:dkaf408.|Biomed Res Int. 2018 Jul 2:2018:3579832.|bioRxiv. 2024 May 10.|Nat Commun. 2022 Mar 2;13 (1) :1116.

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