MAO-A/5-HT2AR-IN-1

MAO-A/5-HT2AR-IN-1

• CAS Number: 2769156-00-3
• UNSPSC Description: MAO-A/5-HT2AR-IN-1 (compound I14) is a potent MAO-A and 5-HT2AR dual inhibitor, with IC50 values of 0.004 and 0.014 μM, respectively. MAO-A/5-HT2AR-IN-1 is a potential antidepressant agent[1].
• Target Antigen: 5-HT Receptor; Monoamine Oxidase
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/mao-a-5-ht2ar-in-1.html
• Solubility: DMF : 5 mg/mL (ultrasonic;warming;heat to 80°C)|DMSO : 20 mg/mL (ultrasonic)
• Smiles: O=C1C2=C(C3=NC=CC4=CC(OCCCCN5CCN(CC5)C6=C(F)C=CC=C6)=CC1=C43)C=CC=C2
• Molecular Weight: 481.56
• References & Citations: [1]Sun X, Li N, et al. Development of MAO-A and 5-HT2AR Dual Inhibitors with Improved Antidepressant Activity. J Med Chem. 2022 Oct 13;65(19):13385-13400.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported