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Bortezomib

CAT: 0421-27028-1Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0421-27028-1Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Potent (Ki, 0.6 nM), specific and reversible proteasome inhibitor; no significant inhibitory activity against other enzymes or receptors. Bortezomib inhibits cell proliferation of H460 cells (human non-small cell lung cancer cell lines) with an IC50 of 0.1 µM and has been associated with suppresion of prostate cancer cell lines with an IC90 of 10 nM.
CAS Number
179324-69-7
Purity
98% by TLC NMR
Solubility
Soluble in DMSO (up to 50 mg/mL) or in Ethanol (up to 35 mg/mL)
Molecular Formula
C19H25BN4O4
Shipping Conditions
-20°C
Storage Conditions
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Calculated Molecular Weight
384.25 Da

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