Kaempferol 3-O-β-D-glucuronide

Kaempferol 3-O-β-D-glucuronide

• CAS Number: 22688-78-4
• UNSPSC Description: Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-glucuronide) is a metabolite of kaempferol that can be taken orally and has anti-inflammatory properties. Kaempferol 3-O-β-D-glucuronide can activate AKT/GSK3β phosphorylation and improve glucose metabolism[1][2][3].
• Target Antigen: Interleukin Related
• Type: Natural Products
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer; Metabolic Disease; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/kaempferol-3-o-β-d-glucuronide.html
• Purity: 99.41
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1OC2=C(C3=CC=C(O)C=C3)OC4=CC(O)=CC(O)=C4C2=O
• Molecular Weight: 462.36
• References & Citations: [1]Khajuria V, et al. Kaempferol-3-o-β-d-glucuronate exhibit potential anti-inflammatory effect in LPS stimulated RAW 264.7 cells and mice model. Int Immunopharmacol. 2018;57:62-71.|[2]Rupayan Bhattacharjee, et al. Extraction and Characterization of Flavonoid Kaempferol-3-Glucuronide from Mango for Treatment of Different Types of Cancers. Great Britain Journals Press. Print ISSN: 2631-8490|[3]Ge Fang, et al. The glucuronide metabolites of kaempferol and quercetin, targeting to the AKT PH domain, activate AKT/GSK3β signaling pathway and improve glucose metabolism. Journal of Functional Foods. Volume 82, July 2021, 104501.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported