Super-TDU (TFA)

• UNSPSC Description:

  Super-TDU TFA is a specific YAP antagonist targeting YAP-TEADs interaction. Super-TDU TFA suppresses tumor growth in gastric cancer mouse model[1].

• Target Antigen:

  YAP

• Type:

  Peptides

• Related Pathways:

  Stem Cell/Wnt

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/super-tdu-tfa.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@@H](C)CC)C(NCC(NCC(N[C@@H](CO)C(NCC(N[C@@H](CC(N)=O)C(N5[C@@H](CCC5)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N[C@@H](CC(N)=O)C(N[C@@H](C(C)C)C(N6[C@@H](CCC6)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](C(C)C)C(N7[C@@H](CCC7)C(N[C@@H](CCSC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N8[C@@H](CCC8)C(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(N[C@@H](CC9=CC=CC=C9)C(N[C@@H](CC%10=CC=CC=C%10)C(N[C@@H](CCCCN)C(N%11[C@@H](CCC%11)C(N%12[C@@H](CCC%12)C(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N.O=C(O)C(F)(F)F

• Molecular Weight:

  5280.92 (free acid)

• References & Citations:

  [1]Jiao S, et al. A peptide mimicking VGLL4 function acts as a YAP antagonist therapy against gastric cancer. Cancer Cell. 2014 Feb 10;25(2):166-80.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported