L 775,606

CAT: 0804-HY-123442Size: 1 EachDry Ice: NoHazardous: No

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Description

L 775,606 is a potent and selective 5-HT1D receptor agonist. L 775,606 can be used to study migraine headache[1].

CAS Number

188400-51-3

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/l-775-606.html

Smiles

FC1=CC(CCN2CCN(CC2)CCCC3=CNC4=C3C=C(C=C4)N5C=NN=C5)=CC=C1

Molecular Formula

C25H29FN6

Molecular Weight

432.54

References & Citations

[1]Prueksaritanont T, et al. Interspecies comparison and role of human cytochrome P450 and flavin-containing monooxygenase in hepatic metabolism of L-775,606, a potent 5-HT (1D) receptor agonist. Xenobiotica. 2000 Jan;30 (1) :47-59.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT1 Receptor

Chemical Information

L-775,606

CAS Number	188400-51-3
PubChem CID	6426760
IUPAC Name	3-[3-[4-[2-(3-fluorophenyl)ethyl]piperazin-1-yl]propyl]-5-(1,2,4-triazol-4-yl)-1H-indole
Molecular Formula	C25H29FN6
Molecular Weight	432.5
XLogP	3.7
Topological Polar Surface Area	53
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	8
Heavy Atom Count	32
Formal Charge	0
Complexity	565

SMILES

C1CN(CCN1CCCC2=CNC3=C2C=C(C=C3)N4C=NN=C4)CCC5=CC(=CC=C5)F

InChI

InChI=1S/C25H29FN6/c26-22-5-1-3-20(15-22)8-10-31-13-11-30(12-14-31)9-2-4-21-17-27-25-7-6-23(16-24(21)25)32-18-28-29-19-32/h1,3,5-7,15-19,27H,2,4,8-14H2

InChIKey

ZUTQCPBDRJBADG-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 188400-51-3

CID: 6426760

Formula: C25H29FN6

MW: 432.5

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	432.5
XLogP3	3.7
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	8
Exact Mass	432.24377311
Monoisotopic Mass	432.24377311
Topological Polar Surface Area	53 Å²
Heavy Atom Count	32
Formal Charge	0
Complexity	565
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
HY-123226	TA-606
HY-19328-01	ACY-775
HY-138077	LSM-775 (maleate)
HY-W952687	CRBN ligand-606
HY-W999600	CRBN ligand-775
HY-RI01840-01	Hsa-miR-606 inhibitor
HY-R01840A-01	Hsa-miR-606 agomir
HY-RI01840A-01	Hsa-miR-606 antagomir
HY-R01840-01	Hsa-miR-606 mimic
HY-W928653	L-Seryl-L-leucyl-L-leucyl-L-lysine

Alternative Products

Catalog	Name
MBS5777487	L-775,606
T28908-01	TA-606
PC1002E-01	AflunoxTM 606
BA4134-5	ACY-775
GTR19195472-01	B 775
RGC98377-01	MSG 606
ABC-TC0169	COLO-775

L 775,606

Chemical Information

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