COQ7-IN-1

CAT: 0804-HY-133033-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-133033-01Size:5 mg

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Description

COQ7-IN-1, a highly potent inhibitor of human coenzyme Q (COQ7), interferes with ubiquinone (UQ) synthesis. COQ7-IN-1 does not disturb physiological cell growth of human normal culture cells. COQ7-IN-1 can be used for the research of the balance between UQ supplementation pathways: de novo UQ synthesis and extracellular UQ uptake[1].

CAS Number

2579696-72-1

UNSPSC

12352005

Target

Mitochondrial Metabolism

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/coq7-in-1.html

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=CC(C2=CC=CC=C2)=NN1C3=CC=C(Cl)C=N3

Molecular Formula

C14H10ClN3O

Molecular Weight

271.70

References & Citations

[1]Keiko Tsuganezawa, et al. Identification of small molecule inhibitors of human COQ7. Bioorg Med Chem. 2020 Jan 1;28 (1) :115182.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Chemical Information

Coq7-IN-1

CAS Number	2579696-72-1
PubChem CID	155981996
IUPAC Name	2-(5-chloro-2-pyridinyl)-5-phenyl-1H-pyrazol-3-one
Molecular Formula	C14H10ClN3O
Molecular Weight	271.70
XLogP	3
Topological Polar Surface Area	45.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
Heavy Atom Count	19
Formal Charge	0
Complexity	379

SMILES

C1=CC=C(C=C1)C2=CC(=O)N(N2)C3=NC=C(C=C3)Cl

InChI

InChI=1S/C14H10ClN3O/c15-11-6-7-13(16-9-11)18-14(19)8-12(17-18)10-4-2-1-3-5-10/h1-9,17H

InChIKey

IRQULQWSSURBFT-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 2579696-72-1

CID: 155981996

Formula: C14H10ClN3O

MW: 271.70

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	271.70
XLogP3	3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
Exact Mass	271.0512396
Monoisotopic Mass	271.0512396
Topological Polar Surface Area	45.2 Å²
Heavy Atom Count	19
Formal Charge	0
Complexity	379
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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Alternative Products

Catalog	Name
T35861-01	COQ7-IN-1
MBS8536494-01	COQ7
338795-01	Ubiquinone biosynthesis Protein COQ7 homolog (COQ7)
70R-16523	COQ7 antibody
T60376-01	COQ7-IN-2
508259	COQ7 discontinued
DF12259-BP	COQ7 Peptide
TS430768P5	COQ7 CytoSection

COQ7-IN-1

Chemical Information

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