ARG1-IN-1 (hydrochloride)

CAT:

804-HY-145331A-02

Size:

10 mg

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UNSPSC Description: ARG1-IN-1 (example 1) hydrochloride is a human arginase 1 inhibitor with an IC50 of 29 nM[1].
Target Antigen: Arginase
Type: Reference compound
Related Pathways: Immunology/Inflammation;Metabolic Enzyme/Protease
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/arg1-in-1-hydrochloride.html
Solubility: 10 mM in DMSO
Smiles: OB(O)CCC[C@H]1[C@@]2([H])[C@@](CNC2)([H])C[C@@]1(N)C(O)=O.[H]Cl
Molecular Weight: 292.57
References & Citations: [1]Mitcheltree MJ, et al. Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy. ACS Med Chem Lett. 2020 Mar 23;11(4):582-588.
Shipping Conditions: Blue Ice
Clinical Information: No Development Reported

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