ARG1-IN-1 (hydrochloride)

• UNSPSC Description:

  ARG1-IN-1 (example 1) hydrochloride is a human arginase 1 inhibitor with an IC50 of 29 nM[1].

• Target Antigen:

  Arginase

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation;Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/arg1-in-1-hydrochloride.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OB(O)CCC[C@H]1[C@@]2([H])[C@@](CNC2)([H])C[C@@]1(N)C(O)=O.[H]Cl

• Molecular Weight:

  292.57

• References & Citations:

  [1]Mitcheltree MJ, et al. Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy. ACS Med Chem Lett. 2020 Mar 23;11(4):582-588.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported